#  Artificial cells 

 



 ##  

  expand\_more  

 
  

 

We worked as part of a larger [collaboration](http://artificialcells.ucsd.edu/) to build an artificial cell that mimics the behavior of a living cell. Our focus is on understanding and mimicking intracellular transport.



 



 

 

 

 

##  Publications 

 



  Download 3 citations  download- [BibTeX](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=bibtex)
- [EndNote X3 XML](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=endnote8)
- [EndNote 7 XML](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=endnote7)
- [Endnote tagged](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=tagged)
- [Marc](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=marc)
- [PubMedId](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=pubmed_id)
- [RIS](/bibcite/export?pager_style=no_pager&number_of_items=6&sort_field=bibcite_year--desc&taxonomy_filters%5Bfield_hwp_c_researchareas%5D%5B0%5D%5Btarget_id%5D=14661&&&format=ris)
 


 

### 2019

Horowitz, V. R.; Chambers, Z. C.; Gozen, I.; Dimiduk, T. G.; Manoharan, V. N.

[Active Colloidal Particles in Emulsion Droplets: A Model System for the Cytoplasm](/publications/active-colloidal-particles-emulsion-droplets-model-system-cytoplasm). *The European Physical Journal Special Topics* **2019**, *227*, 2413-2424.





 

 

Horowitz, V. R.; Chambers, Z. C.; Gozen, I.; Dimiduk, T. G.; Manoharan, V. N.

[Active Colloidal Particles in Emulsion Droplets: A Model System for the Cytoplasm](/publications/active-colloidal-particles-emulsion-droplets-model-system-cytoplasm). *The European Physical Journal Special Topics* **2019**, *227*, 2413-2424.





 

 

 

- [ descriptionPublisher's Version](https://link.springer.com/article/10.1140/epjst/e2019-800026-y)
 
- [ descriptionPublisher's Version](https://link.springer.com/article/10.1140/epjst/e2019-800026-y)
 
 

 



### 2017

Zeravcic, Z.; Manoharan, V. N.; Brenner, M. P.

[Colloquium: Toward Living Matter With Colloidal Particles](/publications/colloquium-toward-living-matter-colloidal-particles). *Reviews of Modern Physics* **2017**, *89* (3), 031001.





 

 

Zeravcic, Z.; Manoharan, V. N.; Brenner, M. P.

[Colloquium: Toward Living Matter With Colloidal Particles](/publications/colloquium-toward-living-matter-colloidal-particles). *Reviews of Modern Physics* **2017**, *89* (3), 031001.





 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](http://dx.doi.org/10.1103/RevModPhys.89.031001)
- [ picture\_as\_pdfZeravcic et al. - 2017 - ...](/sites/g/files/omnuum4256/files/manoharan/files/zeravcic_et_al._-_2017_-_colloquium_toward_living_matter_with_colloidal_pa.pdf)
 
 A fundamental unsolved problem is to understand the differences between inanimate matter and living matter. Although this question might be framed as philosophical, there are many fundamental and practical reasons to pursue the development of synthetic... 

 

 

- [ descriptionPublisher's Version](http://dx.doi.org/10.1103/RevModPhys.89.031001)
- [ picture\_as\_pdfZeravcic et al. - 2017 - ...](/sites/g/files/omnuum4256/files/manoharan/files/zeravcic_et_al._-_2017_-_colloquium_toward_living_matter_with_colloidal_pa.pdf)
 
 

 



### 2013

Bala Subramaniam, A.; Guidotti, G.; Manoharan, V. N.; Stone, H. A.

[Glycans Pattern the Phase Behaviour of Lipid Membranes](/publications/glycans-pattern-phase-behaviour-lipid-membranes). *Nature Materials* **2013**, *12*, 128-133.





 

 

Bala Subramaniam, A.; Guidotti, G.; Manoharan, V. N.; Stone, H. A.

[Glycans Pattern the Phase Behaviour of Lipid Membranes](/publications/glycans-pattern-phase-behaviour-lipid-membranes). *Nature Materials* **2013**, *12*, 128-133.





 

 

 

- add\_circle\_outline do\_not\_disturb\_on Abstract
- [ descriptionPublisher's Version](http://dx.doi.org/10.1038/nmat3492)
- [ picture\_as\_pdfBalaSubramaniam\_NatureMat...](/sites/g/files/omnuum4256/files/manoharan/files/balasubramaniam-naturematerials-2013.pdf)
 
Hydrated networks of glycans (polysaccharides)—in the form of cell walls, periplasms or gel-like matrices—are ubiquitously present adjacent to cellular plasma membranes. Yet, despite their abundance, the function of glycans in the extracellular milieu is...



 

 

- [ descriptionPublisher's Version](http://dx.doi.org/10.1038/nmat3492)
- [ picture\_as\_pdfBalaSubramaniam\_NatureMat...](/sites/g/files/omnuum4256/files/manoharan/files/balasubramaniam-naturematerials-2013.pdf)
 
 

 



 

 

 

 

 

 

##  Alumni 

 



  [### Zachary Chambers

 ](/people/zachary-chambers) <zacharychambers01@college.harvard.edu>Former undergraduate researcher

 

 

 Zach was an undergraduate researcher from Harvard College, where he concentrated in Physics. He worked on the fabrication and characterization of artificial cells. 

 

 

 person 

 

   [### R Feynman

 ](/people/rachel-feynman)Former research intern

 

 

 R was a research intern working on artificial cells, and specifically exploring the influence of micromotors on the kinetics of biologically inspired reactions. They received their Bachelor's degree in physics from Bryn Mawr College in 2015. 

 

 

      ![R](/sites/g/files/omnuum4256/files/styles/hwp_4_5__690x865/public/manoharan/files/rgf.jpg?itok=U2IwGh74) 

 

 

 

   [### İrep Gözen

 ](/people/irep-gozen) <irep@seas.harvard.edu>Former postdoctoral researcher

 

 

 Irep Gözen was a postdoctoral researcher who studied artificial cells and active systems. She received her PhD in 2013 from Chalmers University of Technology in Sweden, where she worked with surface-adhered vesicles to mimic cellular migration, in... 

 

 

      ![Irep](/sites/g/files/omnuum4256/files/styles/hwp_4_5__690x865/public/manoharan/files/gozen.jpg?itok=yqIoTWfT) 

 

 

 

   [### Viva R. Horowitz

 ](/people/viva-horowitz) <viva@physics.harvard.edu>Former postdoctoral researcher

 

 

 Viva was a postdoctoral fellow in Physics who worked on building dynamic artificial cells from the bottom up. Her work explored how to understand cellular processes, particularly intracellular transport, at a physical level by building simple, well... 

 

 

      ![Viva R. Horowitz](/sites/g/files/omnuum4256/files/styles/hwp_4_5__690x865/public/manoharan/files/2013_horowitz.png?itok=4n5IHPo7) 

 

 

 

   [### Danai Montalvan

 ](/people/danai-montalvan) <dmontalvan@seas.harvard.edu>Postdoctoral Fellow

 

 

 Danai was a postdoc working on synthesis and characterization of artificial cells. 

 

 

      ![danai](/sites/g/files/omnuum4256/files/styles/hwp_4_5__690x865/public/manoharan/files/20180327_172257.jpg?itok=K5By9dwM) 

 

 

 

  

 

 

 

 

 



 

 See also:- [ Previous research areas ](/research-projects/previous-research-areas)
- [ Artificial cells ](/research-areas/artificial-cells)
- [ Project descriptions ](/page-categories/project-descriptions)